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Generic for Rapamune* (Sirolimus) is used to prevent rejection of a kidney transplant. It works by suppressing your body’s immune system that can reject a transplanted organ. This medication belongs to a class of drugs known as immunosuppressants. This medicine may also be used to treat other conditions as determined by your doctor.
Sirolimus is indicated for the prophylaxis of organ rejection in patients aged 13 years or older receiving renal transplants. Sirolimus, also known as rapamycin, is a macrolide compound that is used to coat coronary stents, prevent organ transplant rejection and treat a rare lung disease called lymphangioleiomyomatosis. It has immunosuppressant functions in humans and is especially useful in preventing the rejection of kidney transplants. It inhibits activation of T cells and B cells by reducing their sensitivity to interleukin-2 (IL-2) through mTOR inhibition

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Rapamune is an immunosuppressant medication usually prescribed to help minimize the risk of rejection when you receive an organ transplant. Most patients and donor organs are typed and matched as closely as possible to avoid rejection and are advised to take Rapamune or other anti-rejection meds as a precaution. This will help to stop your immune system from rejecting the transplanted organ. Other than being an identical twin receiving an organ from the other twin, there are no 100% matches between organs.

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